1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity connected with bortezomib, a proteasome inhibitor Utilized in the cure of various myeloma. Its synthesis or analyze is critical for making certain the purity and safety of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor during the synthesis of abiraterone acetate, a drug Utilized in the remedy of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-ten-1): A critical compound during the synthesis of imatinib, a drug that targets distinct forms of most cancers, which include Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats different cancers like breast, lung, and prostate most cancers.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are generally intermediates within the synthesis of gemcitabine, an anti-most cancers drug. Their study is crucial for optimizing the manufacturing system and ensuring Paclitaxel side chain acid significant purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is applied to treat breast cancer, and these intermediates are involved with its production.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the remedy of breast most cancers. Many intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-16-nine): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug effective in dealing with cancers for example ovarian, breast, and lung most cancers.
3. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the treatment of colorectal cancer and smaller mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is linked to Cb 7598 the synthesis of adamantane derivatives, that have different apps, which include antiviral Attributes.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for kind two diabetic issues that inhibits the enzyme DPP-four to manage blood sugar stages.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved in the synthesis of various gluconic acid derivatives, that are used in food, pharmaceutical, and industrial applications.
Canagliflozin Intermediate two: A precursor from the synthesis of canagliflozin, a medication utilized to manage form two diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).